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Synthetic reproductive cells will help us understand fertility in 2023

Laboratory-grown sperm, placentas and embryos in animals will help us gauge why some pregnancies don't reach full term, but whether these procedures could one day be safe or even ethical in humans is unclear

By Jason Arunn Murugesu

1 January 2023

A synthetic mouse embryo (left) and a natural mouse embryo (right) show comparable brain and heart formation

A synthetic mouse embryo (left) and a natural mouse embryo (right) showing brain and heart formation

Amadei and Handford

Further advances to the production of synthetic reproductive cells and even organisms in 2023 could boost our understanding of human fertility and why many pregnancies don’t reach full term.

In 2022, such research was carried out in non-human animals, namely rodents. This marked a significant step forward, but also raised the question of whether these procedures would be safe in humans or even ethical.

Between 40 and 60 per cent of human conceptions don’t …

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